For many years, Thai people have understood that consuming dietary supplements such as vitamins, minerals, amino acids, and herbs can help them live healthier lives. Based on this, many healthcare companies view Thailand as a strong market with significant growth potential, thus leading to an increase in the number of dietary supplements being registered with the Food and Drug Administration of Thailand (FDA). However, these companies may be faced with a challenging experience at first, especially if they are accustomed to dealing with regulatory authorities in the U.S., the U.K., or the E.U., where the regulatory requirements are frequently less burdensome. This article examines some of the challenges companies typically face.